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Age

Age

Age and Fertility | Although the direct relationship between the woman’s age and her decreasing reproductive ability is generally well known, women still postpone their first attempts to conceive to later years. Optimal fertile time is between the ages of 20 and 30. Age 25 seems to be optimal. Reproductive ability slowly decreases after age 30 and starts to decline rapidly around age 35. About 10 to 15 years prior to the onset of menopause, the decrease in the quantity of follicles in the ovaries starts to accelerate. At the same time, the blood level of the FSH hormone, which stimulates follicle growth, is increasing. These changes are reflected in the lower quality and potency of the follicles, which leads to decreased egg production. The decrease affects not only the number of eggs in the ovaries, but also their quality and suitability for conception. The menstrual cycle also demonstrates certain changes. It can remain regular, but the first phase (follicular), during which the follicle matures, shortens over time.

Also, a number various complications affecting the reproductive ability occur more frequently with age-the number of menstrual cycles with ovulation decreases; more uterine abnormalities occur (myomas, changes in blood flow, endometrial pathologies, etc.); sexual activity declines; and spontaneous miscarriages occur more frequently.

Age and Assisted Reproduction | From all the couples around 30 years of age, 7% are infertile; from all couples around 40 years of age, 33% are infertile. Over 60% of all women older than 45 are infertile. The success of IVF methods also declines with age. Just under 30% of women after age 40, and only about 10% of women in their mid-forties, give birth successfully after one or more IVF attempts. To this day there are no published studies documenting pregnancy in women 46 years of age and older; generally these women are only able to conceive by using donated eggs.

Polycystic Ovary Syndrome (PCOS) Age Ovulation Disorders Endometriosis Tubal Factor

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